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Chapter 2 - Chapter 2: Proficient-Level Pharmacodynamics and Pharmacokinetics

After reading all the information, Li Jingsheng couldn't help but feel a wave of shame.

When he left the hospital to open the clinic, he was full of ambition, thinking he could achieve great things. However, nine months had passed and his medical skills had hardly improved.

The number of patients he received was pitifully small, mostly cases of colds, fevers, and small injuries.

To improve his medical skills, he needed to follow attending physicians and department heads in large hospitals to treat challenging cases. Slightly more serious illnesses would prompt patients to go to big hospitals, leaving no chance for a clinic doctor like him to practice.

The lack of senior doctors guiding him further slowed his medical skill progress.

Almost all medical students want to enter big hospitals, and there's a reason for that.

Even though he had worked in a big hospital for over five years as a senior resident, his level was still displayed as a junior resident, indicating that his medical skills were much worse than he imagined.

In his youth, he indeed had some inexplicable self-confidence.

Prescription drugs were always his weak spot. Efficacy mainly refers to the effect and mechanism of drugs on the body, whereas pharmacokinetics refers to the process of drug absorption, distribution, biotransformation, and excretion in the body, as well as the pattern of change in drug effect and blood concentration over time.

He understood basic pharmacology, but advanced efficacy and pharmacokinetics were beyond his grasp.

As for combined medication, he didn't even dare to think about it.

Causing a fatality could mean the clinic would shut down in an instant, and the rest of his life would be far from peaceful.

Running his own clinic, the frequency of using medication was very high, and he dreamed of improving his prescription skills.

Even just improving from novice to proficient could significantly enhance his treatment level.

This could greatly increase returning patients and the clinic's reputation, and the safety of medication would also be greatly improved.

The benefits were numerous.

Unfortunately, it's not something that can be improved just by wanting to.

He almost spent part of each day studying, but the results were not satisfactory.

The gap between theory and practice was huge.

Patients don't fall ill according to textbook descriptions.

Diagnosis and medication must be applied flexibly, with comprehensive consideration, and thoroughly deliberated.

Now, with the sudden emergence of such an information panel, he realized that he might have struck a stroke of luck, opening a system or something like a cheat. Once he grasped the knack, improving his prescription skills in the future would be much easier.

He continued to study other information below.

Skills mainly referred to surgery, which was the weak point for most doctors. Many chief physicians couldn't even perform simple sutures well, let alone high-risk open abdominal or thoracic surgeries.

The training cycle for surgical doctors usually takes ten years.

A talented medical student needs to follow a teacher in the operating room for more than ten years to achieve a minor achievement. Only then can they independently perform second-level or below surgeries.

Surgical doctors in major hospitals have always been in short supply because the training cycle is too long.

Talented individuals are even rarer than hen's teeth.

Li Jingsheng had worked in a hospital for six years but never dared to operate on patients, not even daring to remove a small tumor. At most, he would help patients suture minor wounds.

The key was that he didn't suture well.

The wounds he sutured would almost always leave unsightly, hideous scars after healing.

The only advantage was that it was cheap.

Nine out of ten people who came to the clinic for treatment were looking for affordability.

What is the purpose of life value?

Does he only have 13 years of life left? His nerves were tense, at not even thirty years old, this would mean he wouldn't live past fifty?

After some exploration, he quickly discovered it was just a false alarm.

Life value could be allocated to any item of level, diagnosis, prescriptions, or skills.

With this discovery, Li Jingsheng was elated.

He wanted to improve every skill, but with only 13 life points, after careful consideration, he decided to first enhance the efficacy and pharmacokinetics abilities of prescriptions.

The current efficacy was entry-level at 6.4/10; it only required 4 points to advance to proficient level.

Without hesitation, he decisively added 4 points to it.

In an instant, his life value dropped from 13 points to 9, but his efficacy advanced from entry-level to proficient at 10.4/100.

No matter how many times he burned the midnight oil reading, he couldn't advance it, but now it advanced to proficient in an instant, and he experienced an unprecedented thrill.

The moment his efficacy advanced to proficient, it was as if his mind suddenly became enlightened.

He gained a completely new understanding and comprehension of the clinical effects, side effects, and toxic reactions of many common drugs.

For example, the most commonly used penicillin is known as penicillin, and its function is bactericidal.

Previously, his concept of its use was very vague.

For wound infections, tonsillitis, pneumonia, boils, and so on, as long as it was a bacterial infection, Li Jingsheng would generally use it.

Treating all ailments with a single remedy was actually a reflection of poor skill.

Now that his efficacy was advanced to proficient, his clinical use of penicillin had become much clearer.

Penicillin had developed into dozens of types, each with different advantages and disadvantages, and different bactericidal effects on various bacteria.

For example, if a patient now presents with stomach pain from eating undercooked chicken, and it is identified as a Salmonella infection, he would choose methicillin or oxacillin penicillins.

This is because these penicillins are highly enzyme-resistant and effective against certain Gram-negative bacilli like Escherichia coli, Klebsiella, and Salmonella, but they are less effective against Pseudomonas aeruginosa.

Previously, achieving such a precise level of medication was impossible.

This was also why, for the same disease, some doctors achieve obvious effects with medication, quickly curing the disease, while others have unsatisfactory results or recurring illnesses.

In addition to more precise medication, he also gained a deeper understanding of various drugs' side effects, residual effects, and teratogenic effects.

Considering only drug efficacy wasn't enough; one also had to consider the drug's side effects.

For example, there are many drugs pregnant women cannot take, as they may cause fetal deformities, or even lead to miscarriage. Similarly, patients with heart stents or vascular stents need to be extremely cautious when taking hemostatic drugs.

Medication has strict requirements for different patients.

After advancing to the proficient level in efficacy, medication safety, and treatment effects for patients would greatly improve.

Experiencing the significant benefits brought by advancing to proficient in efficacy, Li Jingsheng couldn't help but be excited.

He could already see the light of a turnaround in his life.

This time, without even thinking, he directly allocated 8 points of life value to pharmacokinetics.

Instantly breaking through from entry-level to proficient.

Pharmacokinetics proficient 10.3/100.

Pharmacokinetics' full name is pharmacokinetics, and its function is no less than that of efficacy.

After medication is taken, whether it can be absorbed by the body, its distribution, biochemical conversion, and excretion in the body all belong to pharmacokinetics. Especially the pattern of how blood concentration changes over time relates directly to medication safety.

Infusion accidents leading to death in small clinics occur from time to time.

These are often caused by doctors with poor pharmacokinetics levels blindly pursuing efficacy.

For example, a duodenal ulcer can be treated with famotidine. An adult dosage is 20mg*5, administered intravenously. This drug has a characteristic of extremely slow metabolism and prolonged efficacy. If a doctor's pharmacokinetics level is insufficient, administering infusions too quickly or re-dosing in a short period might cause severe consequences.

For most clinics, a single accident could be the end.

Improving pharmacokinetics is essential.

It can further improve his medication level and safety factor.

In many small clinics, doctors only have entry-level efficacy and pharmacokinetics. Now Li Jingsheng had advanced these two medical skills to proficient level, which was a major competitive advantage.

He dared to use drugs others wouldn't.

For the same illness, while other clinics' medication might take a week to cure, his might allow patients to recover in three days.

Moreover, the doses would be more precise, and costs would be lower.

Medication would be more accurate.

Life value was indeed a good thing; in the blink of an eye, he had used it up, leaving only 1 point.

He needed to find ways to earn more.

Because there were still many medical skills to enhance, especially surgical skills; even tying knots was problematic, which severely affected suture quality.

"Miss, miss, don't leave! We can do infusions here; we can start right now."

The voice of nurse Tang Ping trying to retain a patient brought Li Jingsheng back to reality.

Administering an infusion for a patient could earn at least eighty yuan; doing it twice would be one hundred sixty yuan.

She was obviously unwilling to let them go easily.

Sometimes Tang Ping even felt anxious for the boss; salaries couldn't be paid, yet he always thought of patients. In the end, patients even mocked the clinic's medical skills as inferior to others.

Being too honest in business was a disadvantage.

"Really?"

The patient turned, looking at Tang Ping with half-belief.

"Of course, it's true. This is my practice certificate, issued by the health supervisory department, nationally certified." Tang Ping was already very skilled at persuading this type of patient.

With such an honest boss, if she wasn't a bit slick, she'd be left out in the cold.

"How much does an infusion cost here? The results won't be worse than Quick Recovery Clinic, will they?"

The patient apparently believed somewhat, hesitating by holding the doorknob.

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